{"id":4686,"date":"2016-10-14T07:05:32","date_gmt":"2016-10-14T11:05:32","guid":{"rendered":"https:\/\/medicarereport.org\/?p=4686"},"modified":"2016-10-13T08:08:12","modified_gmt":"2016-10-13T12:08:12","slug":"a-crispr-based-fix-for-human-sickle-cells-shows-promise-in-mice","status":"publish","type":"post","link":"https:\/\/medicarereport.org\/?p=4686","title":{"rendered":"A CRISPR-based fix for human sickle cells shows promise in mice"},"content":{"rendered":"<p>(By Sharon Begley for ST<em>A<\/em>T)<\/p>\n<p><span class=\"big-cap\">S<\/span>cientists have taken an important step toward using CRISPR-Cas9 genome-editing to cure <a href=\"https:\/\/www.statnews.com\/2016\/05\/19\/sickle-cell-disease-cure\/\" target=\"_blank\">sickle cell disease<\/a><sup class=\"footnote\">1<\/sup>, repairing the disease-causing mutation in blood-forming cells taken from patients. Some edited cells, injected into lab mice, both survived in the animals\u2019 bone marrow and\u00a0turned into red blood cells \u2014 a hint that CRISPR\u2019d cells would\u00a0\u00a0would produce healthy hemoglobin\u00a0in people. This is the first such experiment to get levels of healthy hemoglobin that might be high enough to cure patients. <a href=\"https:\/\/www.statnews.com\/2016\/10\/12\/crispr-sickle-cell-mouse\/\" target=\"_blank\">Continue reading article here&#8230;&#8230;<\/a><\/p>\n<p><a href=\"https:\/\/medicarereport.org\/wp-content\/uploads\/2016\/09\/STAT-Logo.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-4372\" src=\"https:\/\/medicarereport.org\/wp-content\/uploads\/2016\/09\/STAT-Logo-300x32.png\" alt=\"stat-logo\" width=\"300\" height=\"32\" srcset=\"https:\/\/medicarereport.org\/wp-content\/uploads\/2016\/09\/STAT-Logo-300x32.png 300w, https:\/\/medicarereport.org\/wp-content\/uploads\/2016\/09\/STAT-Logo.png 453w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<pre><strong>Notice<\/strong>: The link provided above connects readers to the full content of the posted article. The URL (internet address) for this link is valid on the posted date; medicarereport.org cannot guarantee the duration of the link\u2019s validity. Also, the opinions expressed in these postings are the viewpoints of the original source and are not explicitly endorsed by AMAC, Inc.; the AMAC Foundation, Inc.; or medicarereport.org.<\/pre>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>(By Sharon Begley for STAT) Scientists have taken an important step toward using CRISPR-Cas9 genome-editing to cure sickle cell disease1,<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12,14],"tags":[],"class_list":["post-4686","post","type-post","status-publish","format-standard","hentry","category-health-care-general","category-medical-technology"],"_links":{"self":[{"href":"https:\/\/medicarereport.org\/index.php?rest_route=\/wp\/v2\/posts\/4686","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicarereport.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicarereport.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicarereport.org\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/medicarereport.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4686"}],"version-history":[{"count":1,"href":"https:\/\/medicarereport.org\/index.php?rest_route=\/wp\/v2\/posts\/4686\/revisions"}],"predecessor-version":[{"id":4687,"href":"https:\/\/medicarereport.org\/index.php?rest_route=\/wp\/v2\/posts\/4686\/revisions\/4687"}],"wp:attachment":[{"href":"https:\/\/medicarereport.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4686"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicarereport.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4686"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicarereport.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4686"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}