Genetic clues found for cognitive resilience to Alzheimer’s disease

(Source – www.nia.nih.gov/news)

Three genetic variants may be associated with cognitive resilience in Alzheimer’s disease, according to the results of a large, genome-wide association study (GWAS). The study, funded in part by NIA, identified novel genetic variants, genes and biological pathways that are associated with cognitive resilience, or protection, from memory and thinking issues connected to Alzheimer’s disease despite the presence of neuropathology in the brain. Notably, the researchers did not see a connection between cognitive resilience and the genetic variations in the APOE gene that are associated with a higher risk of developing Alzheimer’s. The findings, published in Brain, provide new insights into the biology of cognitive resilience and may suggest new pathways and targets for development of Alzheimer’s treatments.  Continue reading here…

Notice: The link provided above connects readers to the full content of the posted article. The URL (internet address) for this link is valid on the posted date; medicarereport.org cannot guarantee the duration of the link’s validity. Also, the opinions expressed in these postings are the viewpoints of the original source and are not explicitly endorsed by AMAC, Inc.; the AMAC Foundation, Inc.; or medicarereport.org